Article
Undifferentiated nasopharyngeal carcinoma from a nonendemic area: protective role of HLA allele products presenting conserved EBV epitopes.
International journal of cancer - 15 Sept 2009
Pasini Elisa, Caggiari Laura, Dal Maso Luigino, Martorelli Debora, Guidoboni Massimo, Vaccher Emanuela, Barzan Luigi, Franchin Giovanni, Gloghini Annunziata, De Re Valli, Sacchi Nicoletta, Serraino Diego, Carbone Antonino, Rosato Antonio, Dolcetti Riccardo
Abstract excerpt
The role of genetic factors involved in the development of undifferentiated nasopharyngeal carcinoma (UNPC) in nonendemic areas has been poorly investigated. High-resolution human leukocyte antigen (HLA) class I genotyping carried out in 82 Italian UNPC patients and 286 bone marrow donors born in the same province showed that A*0201, B*1801, and B*3501, known to efficiently present Epstein-Barr virus...
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