Article
[Pathophysiology of restless legs syndrome].
Brain and nerve = Shinkei kenkyu no shinpo - 1 May 2009
Miyamoto Masayuki, Miyamoto Tomoyuki, Iwanami Masaoki, Suzuki Keisuke, Hirata Koichi
Abstract excerpt
Restless legs syndrome (RLS) is a sensorimotor disorder that is frequently associated with periodic leg movements (PLMS). RLS is generally considered to be a central nervous system (CNS)-related disorder although no specific lesion has been found to be associated with the syndrome. Reduced intracortical inhibition has been demonstrated in RLS by transcranial magnetic stimulation. Some MRI studies have revealed...
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