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Article

Somatic cAMP signaling regulates MSP-dependent oocyte growth and meiotic maturation in<i>C. elegans</i>

5 Jun 2009

Abstract excerpt

Soma-germline interactions control fertility at many levels, including stem cell proliferation, meiosis and gametogenesis, yet the nature of these fundamental signaling mechanisms and their potential evolutionary conservation are incompletely understood. In C. elegans, a sperm-sensing mechanism regulates oocyte meiotic maturation and ovulation, tightly coordinating sperm availability and fertilization. Sperm...

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PMID: 19502483
DOI: 10.1242/dev.034595

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