Article
CD34+ cells in maternal placental blood are mainly fetal in origin and express endothelial markers.
Laboratory investigation; a journal of technical methods and pathology - 1 Aug 2009
Parant Olivier, Dubernard Gil, Challier Jean-Claude, Oster Michèle, Uzan Serge, Aractingi Sélim, Khosrotehrani Kiarash
Abstract excerpt
Fetal CD34+ cells enter the maternal circulation during pregnancy and may persist for decades. These cells are usually depicted as hematopoietic stem/progenitor cells. Our objective was to further determine the phenotype of fetal chimeric CD34+ cells in placental maternal blood from the intervillous space (IVS). Human healthy term placentas were analyzed (n=9). All fetuses were male. CD34+ cells were identified...
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