Article
Complement in human diseases: Lessons from complement deficiencies.
Molecular immunology - 1 Sept 2009
Botto Marina, Kirschfink Michael, Macor Paolo, Pickering Matthew C, Würzner Reinhard, Tedesco Francesco
Abstract excerpt
Complement deficient cases reported in the second half of the last century have been of great help in defining the role of complement in host defence. Surveys of the deficient individuals have been instrumental in the recognition of the clinical consequences of the deficiencies. This review focuses on the analysis of the diseases associated with the deficiencies of the various components and regulators of the...
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