Article
RNA binding by the brome mosaic virus capsid protein and the regulation of viral RNA accumulation.
Journal of molecular biology - 14 Aug 2009
Yi Guanghui, Vaughan Robert C, Yarbrough Ian, Dharmaiah S, Kao C Cheng
Abstract excerpt
Viral capsid proteins (CPs) can regulate gene expression and encapsulate viral RNAs. Low-level expression of the brome mosaic virus (BMV) CP was found to stimulate viral RNA accumulation, while higher levels inhibited translation and BMV RNA replication. Regulation of translation acts through an RNA element named the B box, which is also critical for the replicase assembly. The BMV CP has also been shown to...
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