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Article

Antidepressant-induced jitteriness/anxiety syndrome: systematic review.

The British journal of psychiatry : the journal of mental science - 1 Jun 2009

Sinclair Lindsey I, Christmas David M, Hood Sean D, Potokar John P, Robertson Andrea, Isaac Andrew, Srivastava Shrikant, Nutt David J, Davies Simon J C

Abstract excerpt

BACKGROUND: Early worsening of anxiety, agitation and irritability are thought to be common among people commencing antidepressants, especially for anxiety disorders. This phenomenon, which may be termed jitteriness/anxiety syndrome, is cited as an explanation for early treatment failure and caution in using selective serotonin reuptake inhibitors (SSRIs). However, we believe that it is inconsistently defined and...

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Source

Identifiers

PMID: 19478285
DOI: 10.1192/bjp.bp.107.048371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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