Article
Combinatorial algorithms for structural variation detection in high-throughput sequenced genomes.
Genome research - 1 Jul 2009
Hormozdiari Fereydoun, Alkan Can, Eichler Evan E, Sahinalp S Cenk
Abstract excerpt
Recent studies show that along with single nucleotide polymorphisms and small indels, larger structural variants among human individuals are common. The Human Genome Structural Variation Project aims to identify and classify deletions, insertions, and inversions (>5 Kbp) in a small number of normal individuals with a fosmid-based paired-end sequencing approach using traditional sequencing technologies. The...
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