Article
Molecular basis of prolidase (peptidase D) deficiency.
Molecular biology & medicine - 1 Feb 1991
Endo F, Matsuda I
Abstract excerpt
Human prolidase (PEPD, iminodipeptidase, EC 3.4.13.9) and related deficiencies were analyzed in terms of the nature and molecular biology of the enzyme and the molecular events seen in patients with this deficiency. The analyses were based on findings concerning isolation of the enzyme, development of specific antibodies and molecular cloning of cDNA and genome DNA of human prolidase. The studies revealed that...
Topics
- Base Sequence
- Chromosome Mapping
- Cloning, Molecular
- DNA
- DNA Mutational Analysis
- Dipeptidases
- Humans
- Molecular Sequence Data
- Phenotype