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Article

Meta-mining of Neuroblastoma and Neuroblast Gene Expression Profiles Reveals Candidate Therapeutic Compounds

12 May 2009

Abstract excerpt

PURPOSE: Neuroblastoma is a heterogeneous childhood tumor with poor survival outcome for the aggressive type despite intensive multimodal therapies. In this study, we aimed to identify new treatment options for neuroblastoma based on integrative genomic analysis. EXPERIMENTAL DESIGN: The Connectivity Map is a database comprising expression profiles in response to known therapeutic compounds. This renders it a...

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PMID: 19435837
DOI: 10.1158/1078-0432.ccr-08-2699

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