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Human Pregnancy Up-Regulates Tim-3 in Innate Immune Cells for Systemic Immunity

1 May 2009

Abstract excerpt

Pregnant women have both the local immune tolerance at the maternal-fetal interface and the systemic immune defense against pathogens. To date, regardless of the extensive investigation on the maternal-fetal immune tolerance, the maintenance of systemic immune defense in pregnant women still remains poorly understood. In the present study, we demonstrate that the immunoregulatory molecule T cell Ig and mucin...

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PMID: 19414817
DOI: 10.4049/jimmunol.0803876

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