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Article

Cerebral primitive neuroectodermal tumor in an adult with a heterozygous MSH2 mutation.

Nature reviews. Clinical oncology - 1 May 2009

Jeans Alexander F, Frayling Ian, Jasani Bharat, Side Lucy, Blesing Claire, Ansorge Olaf

Abstract excerpt

BACKGROUND: A 37-year-old woman presented with a supratentorial cerebral mass, which was diagnosed histologically as a primitive neuroectodermal tumor. She had been treated for rectal adenocarcinoma 7 years previously. A family history revealed a young-onset colorectal carcinoma in the patient's father. INVESTIGATIONS: Immunohistochemical analysis for DNA mismatch repair proteins, germline mutation analysis of...

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Source

Identifiers

PMID: 19390556
DOI: 10.1038/nrclinonc.2009.35

Genes

MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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