Article
[The regulation of peroxisomal matrix enzymes (alcohol oxidase and catalase) formation by the product of the gene Mth1 in methylotrophic yeast Pichia methanolica].
Prikladnaia biokhimiia i mikrobiologiia - 1 Jan 2000
Leonovich O A, Kurales Iu A, Dutova T A, Isakova E P, Deriabina Iu I, Rabinovich Ia M
Abstract excerpt
Two independent mutant strains of methylotrophic yeast Pichia methanolica (mth1 arg1 and mth2 arg4) from the initial line 616 (ade1 ade5) were investigated. The mutant strains possessed defects in genes MTH1 and MTH2 which resulted in the inability to assimilate methanol as a sole carbon source and the increased activity of alcohol oxidase (AO). The function of the AUG2 gene encoding one of the subunits of AO and...
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