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Article

Molecular screening of deafness in Algeria: high genetic heterogeneity involving DFNB1 and the Usher loci, DFNB2/USH1B, DFNB12/USH1D and DFNB23/USH1F.

European journal of medical genetics - 1 Jan 2000

Ammar-Khodja Fatima, Faugère Valérie, Baux David, Giannesini Claire, Léonard Susana, Makrelouf Mohamed, Malek Rahia, Djennaoui Djamel, Zenati Akila, Claustres Mireille, Roux Anne-Françoise

Abstract excerpt

A systematic approach, involving haplotyping and genotyping, to the molecular diagnosis of non-syndromic deafness within 50 families and 9 sporadic cases from Algeria is described. Mutations at the DFNB1 locus (encompassing the GJB2 and GJB6 genes) are responsible for more than half of autosomal recessive prelingual non-syndromic deafness in various populations. A c.35delG mutation can account for up to 85% of...

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Source

Identifiers

PMID: 19375528
DOI: 10.1016/j.ejmg.2009.03.018

Genes

GJB6
GJB2
CDH23
PCDH15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular screening of deafness in Algeria: high genetic heterogeneity involving DFNB1 and the Usher loci, DFNB2/USH1B, DFNB12/USH1D and DFNB23/USH1F.PMID 19375528Read ↗

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