Article
Accumulation of mitochondrial genome variations in Persian LQTS patients: a possible risk factor?
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology - 1 Jan 2000
Khatami Mehri, Houshmand Massoud, Sadeghizadeh Majid, Eftekharzadeh Mahmood, Heidari Mohammad Mehdi, Saber Siamak, Banihashemi Kambiz, Scheiber-Mojdehkar Barbara
Abstract excerpt
BACKGROUND: Long QT syndrome (LQTS) is among arrhythmia disorders of the heart that causes sudden cardiac death in young individuals. As yet, most of investigations have focused on nuclear genome for finding genetic defects in this disorder, but some of the cases with LQTS cannot be explained by mutations of identified genes. On the other hand, it has been reported that the activity of ion channels in...
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