Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The 5-HTTLPR polymorphism modulates the association of serious life events (SLE) and impulsivity in patients with Borderline Personality Disorder.

Journal of psychiatric research - 1 Sept 2009

Wagner Stefanie, Baskaya Omür, Lieb Klaus, Dahmen Norbert, Tadić André

Abstract excerpt

BACKGROUND: Impulsivity belongs to the key features of Borderline Personality Disorder (BPD). It has been linked to altered serotoninergic neurotransmission and, genetically, to an over-representation of the short (S) allele of the serotonin transporter promoter-linked polymorphic region polymorphism (5-HTTLPR). On the other hand, serious life events (SLE) are of major importance in the development of BPD....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Borderline Personality Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Impulsive Behavior

Share to Regression Analysis

Share to Serotonin Plasma Membrane Transport Proteins

Share to Young Adult

Source

Identifiers

PMID: 19358998
DOI: 10.1016/j.jpsychires.2009.03.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The 5-HTTLPR polymorphism modulates the association of serious life events (SLE) and impulsivity in patients with Borderline Personality Disorder.PMID 19358998Read ↗

The catechol o-methyltransferase (COMT) val(158)met polymorphism modulates the association of serious life events (SLE) and impulsive aggression in female patients with borderline personality disorder (BPD).Semantic proximity Read ↗

Modulatory role of the brain-derived neurotrophic factor Val66Met polymorphism on the effects of serious life events on impulsive aggression in borderline personality disorder.Semantic proximity Read ↗

Interaction between gene variants of the serotonin transporter promoter region (5-HTTLPR) and catechol O-methyltransferase (COMT) in borderline personality disorder.Semantic proximity Read ↗

The serotonin transporter gene polymorphism (5-HTTLPR) and affective symptoms among women diagnosed with borderline personality disorder.Semantic proximity Read ↗

The effect of 5-HTT gene promoter polymorphism on impulsivity depends on family relations in girls.Semantic proximity Read ↗

Serotonin system gene polymorphisms are associated with impulsivity in a context dependent manner.Semantic proximity Read ↗

Interaction between tryptophan hydroxylase I polymorphisms and childhood abuse is associated with increased risk for borderline personality disorder in adulthood.Semantic proximity Read ↗

Association between a serotonin transporter promoter polymorphism (5HTTLPR) and personality disorder traits in a community sample.Semantic proximity Read ↗

Association between 5-HTTLPR and Borderline Personality Disorder Traits among YouthSemantic proximity Read ↗

Life events and borderline personality features: the influence of gene-environment interaction and gene-environment correlation.Semantic proximity Read ↗

Association analysis between gene variants of the tyrosine hydroxylase and the serotonin transporter in borderline personality disorder.Semantic proximity Read ↗

Genetics of borderline personality disorder: systematic review and proposal of an integrative model.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.