Article
ALA-PDT results in phenotypic changes and decreased cellular invasion in surviving cancer cells.
Lasers in surgery and medicine - 1 Apr 2009
Tsai Tsuimin, Ji Hong Tai, Chiang Pei-Chi, Chou Ruey-Hwang, Chang Wun-Shaing Wayne, Chen Chin-Tin
Abstract excerpt
BACKGROUND AND OBJECTIVES: The mechanisms of photodynamic therapy (PDT) have been studied on the cellular and tissue levels. However, the cellular behaviors of cancer cells survived from PDT are still not clear. This study attempted to investigate the influence of 5-aminolevulinic acid (ALA)-based PDT on the invasion ability as well as molecular changes in surviving cancer cells and their progeny. MATERIALS AND...
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