Article
Molecular phenotypes distinguish patients with relatively stable from progressive idiopathic pulmonary fibrosis (IPF).
PloS one - 1 Jan 2009
Boon Kathy, Bailey Nathaniel W, Yang Jun, Steel Mark P, Groshong Steve, Kervitsky Dolly, Brown Kevin K, Schwarz Marvin I, Schwartz David A
Abstract excerpt
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic interstitial lung disease that is unresponsive to current therapy and often leads to death. However, the rate of disease progression differs among patients. We hypothesized that comparing the gene expression profiles between patients with stable disease and those in which the disease progressed rapidly will lead to biomarker discovery and...
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