Article
Mutations in the human homeobox MSX1 gene in the congenital lack of permanent teeth.
The Tohoku journal of experimental medicine - 1 Apr 2009
Pawlowska Elzbieta, Janik-Papis Katarzyna, Wisniewska-Jarosinska Maria, Szczepanska Joanna, Blasiak Janusz
Abstract excerpt
Tooth agenesis is the congenital lack of permanent teeth, which is called oligodontia, when the number of missing teeth is 6 or more. Oligodontia affects more than 1 of 100 humans, but its pathogenesis is largely unknown. Tooth genesis depends on the complex interactions between environmental and genetic factors. The MSX1 gene, a member of homeobox gene family, encodes a DNA-binding protein, which is involved in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.