Article
PRKCSH genetic mutation was not found in Taiwanese patients with polycystic liver disease.
Digestive diseases and sciences - 1 Mar 2010
Yang An-Ming, Shih Shou-Chuan, Chu Cheng-Hsin, Wang Tsang-En, Yang Wei-Shiung
Abstract excerpt
Polycystic liver disease (PCLD) without polycystic kidney is infrequent in clinical setting. Family clustering is found in patients with PCLD, and it is inherited in an autosomal dominant fashion. Through positional cloning in North America and Europe (mostly in Dutch and Finnish descents), mutations in PRKCSH gene on chromosome 19 were found to be responsible for the disease. We investigated the prevalence of...
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