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Article

Mutational meltdown in primary endosymbionts: selection limits Muller's ratchet.

PloS one - 1 Jan 2009

Allen Julie M, Light Jessica E, Perotti M Alejandra, Braig Henk R, Reed David L

Abstract excerpt

BACKGROUND: Primary bacterial endosymbionts of insects (p-endosymbionts) are thought to be undergoing the process of Muller's ratchet where they accrue slightly deleterious mutations due to genetic drift in small populations with negligible recombination rates. If this process were to go unchecked over time, theory predicts mutational meltdown and eventual extinction. Although genome degradation is common among...

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Identifiers

PMID: 19305500
DOI: 10.1371/journal.pone.0004969
PMCID: PMC2654755

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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