Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reliability of real-time reverse-transcription PCR in clinical diagnostics: gold standard or substandard?

1 Mar 2009

Abstract excerpt

Molecular diagnostics is one of the major growth areas of modern medicine, with real-time PCR established as a qualitative and quantitative technology that is rapid, accurate and sensitive. The sequencing of the human genome, comprehensive genomic, mRNA and miRNA expression profiling of numerous cancer types, the ongoing identification of disease-associated polymorphisms and the expanding availability of genomic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Molecular Biology Techniques and Applications
Share to Viral gastroenteritis research and epidemiology
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19298142
DOI: 10.1586/14737159.9.2.187

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reliability of real-time reverse-transcription PCR in clinical diagnostics: gold standard or substandard?PMID 19298142Read ↗

Real-time reverse transcription PCR (qRT-PCR) and its potential use in clinical diagnosisSemantic proximity Read ↗

Quantitative Real-Time PCR Is Not More Sensitive than “Conventional” PCRSemantic proximity Read ↗

RT-qPCR Diagnostics: The “Drosten” Sars-Cov-2 Assay ParadigmSemantic proximity Read ↗

Real-time PCR: overview and applications.Semantic proximity Read ↗

Real-time PCR in virologySemantic proximity Read ↗

Development of quantitative gene-specific real-time RT-PCR assays for the detection of measles virus in clinical specimensSemantic proximity Read ↗

The PCR Revolution: Basic Technologies and ApplicationsSemantic proximity Read ↗

Analysis of external quality assessment samples revealed crucial performance differences between commercial RT-PCR assays for SARS-CoV-2 detection when taking extraction methods and real-time-PCR instruments into accountSemantic proximity Read ↗

Real-time quantitative polymerase chain reaction: a potential tool for genetic analysis in neuropathology.Semantic proximity Read ↗

Real-time PCR in the microbiology laboratory.Semantic proximity Read ↗

Positive control synthesis method for COVID-19 diagnosis by one-step real-time RT-PCRSemantic proximity Read ↗

Ribosomal RNA: Nature's own polymerase-amplified target for diagnosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.