Article
Effect of Fas -670 A/G gene polymorphism on corneal allograft endothelial rejection.
Iranian journal of immunology : IJI - 1 Mar 2009
Jahadi Hosseini Hamid Reza, Kamali Sarvestani Eskandar, Akbari Mitra, Mosallaei Mahnaz
Abstract excerpt
BACKGROUND: Human cornea expresses functional Fas-ligand capable of killing Fas+ activated lymphocytes. Fas expression is partly regulated by -670 A/G polymorphism in the promoter region of Fas gene. OBJECTIVE: The aim of the present study is to determine the association between Fas-670A/G polymorphism and survival of corneal transplantation. METHODS: In 276 graft recipients who mainly underwent penetrating...
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