Article
A population-based assessment of the familial component of acute kidney allograft rejection.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Aug 2009
Goldfarb-Rumyantzev Alexander S, Shihab Fuad, Emerson Lyska, Mineau Geraldine, Schaefer Carole, Tang Hongying, Hunter Cheri, Naiman Natalie, Smith Lonnie, Kerber Richard
Abstract excerpt
BACKGROUND: The genetic determinants of acute kidney transplant rejection (AR) are not well studied, and familial aggregation has never been demonstrated. The goal of this retrospective case-control study was to exploit the unique nature of the Utah Population Database (UPDB) to evaluate if AR or rejection-free survival aggregates in families. METHODS: We identified 891 recipients with genealogy data in the UPDB...
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