Thrombosis in Japanese patients with Fabry disease.

Abstract excerpt

Fabry disease is an X-linked lysosomal storage disease resulting from deficient activity of the enzyme alpha-galactosidase (alpha-Gal) A. It has been postulated that the accumulation of globotriaosylceramide in the endothelial cells of blood vessels may lead to thrombosis of the brain and other tissues. Recently, enzyme replacement therapy (ERT) for Fabry disease is available. A high incidence of thrombotic...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to alpha-Galactosidase
• Share to Brain Infarction