First insight into genetic diversity of the Mycobacterium tuberculosis complex in Albania obtained by multilocus variable-number tandem-repeat analysis and spoligotyping reveals the presence of beijing multidrug-resistant isolates.

doi:10.1128/JCM.02284-08

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Article

First insight into genetic diversity of the Mycobacterium tuberculosis complex in Albania obtained by multilocus variable-number tandem-repeat analysis and spoligotyping reveals the presence of beijing multidrug-resistant isolates.

Journal of clinical microbiology - 1 May 2009

Tafaj Silva, Zhang Jian, Hauck Yolande, Pourcel Christine, Hafizi Hasan, Zoraqi Grigor, Sola Christophe

Abstract excerpt

We characterized a set of 100 Mycobacterium tuberculosis complex clinical isolates from tuberculosis (TB) patients in Albania, typing them with a 24-locus variable-number tandem-repeat-spoligotyping scheme. Depending on the cluster definition, 43 to 49 patients were distributed into 15 to 16 clusters which were likely to be epidemiologically linked, indicative of a recent transmission rate of 28 to 34%. This...

Topics

Albania
Bacterial Typing Techniques
Cluster Analysis
DNA Fingerprinting
DNA, Bacterial
DNA-Directed RNA Polymerases
Female
Genetic Variation
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Minisatellite Repeats

Molecular Epidemiology

Mutation, Missense

Mycobacterium tuberculosis

Tuberculosis

Source

Open in PubMed Open full text

Identifiers

PMID: 19279172
DOI: 10.1128/JCM.02284-08
PMCID: PMC2681852

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-19279172-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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