Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The impact of spermine synthase (SMS) mutations on brain morphology.

Neurogenetics - 1 Oct 2009

Kesler Shelli R, Schwartz Charles, Stevenson Roger E, Reiss Allan L

Abstract excerpt

Snyder-Robinson syndrome (SRS) is a form of X-linked mental retardation resulting from mutations in spermine synthase (SMS), which impact neurodevelopment and cognitive outcome. We obtained cerebral, cerebellum, hippocampus, and red nucleus volumes from two males with SRS and 24 age- and gender-matched typically developing controls using volumetric neuroimaging analyses. Total brain volume was enlarged in males...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abnormalities, Multiple
Share to Adolescent
Share to Brain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Magnetic Resonance Imaging

Share to Mutation

Share to Syndrome

Share to X-Linked Intellectual Disability

Source

Open in PubMed Open full text

Identifiers

PMID: 19277733
DOI: 10.1007/s10048-009-0184-2
PMCID: PMC3061622

Genes

SMS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The impact of spermine synthase (SMS) mutations on brain morphology.PMID 19277733Read ↗

Impaired polyamine metabolism causes behavioral and neuroanatomical defects in a novel mouse model of Snyder-Robinson SyndromeSemantic proximity Read ↗

Advances in research on the neurological and neuropsychiatric phenotype of Klinefelter syndrome.Semantic proximity Read ↗

Spermine synthase deficiency resulting in X-linked intellectual disability (Snyder-Robinson syndrome).Semantic proximity Read ↗

Impaired osteoblast and osteoclast function characterize the osteoporosis of Snyder - Robinson syndrome.Semantic proximity Read ↗

Reduced Brain Volume and White Matter Alterations in Shank3-Deficient RatsSemantic proximity Read ↗

Abnormal brain magnetic resonance imaging in two patients with Smith-Magenis syndrome.Semantic proximity Read ↗

Polyamine Homeostasis in Snyder-Robinson SyndromeSemantic proximity Read ↗

Cognitive Profiles and Brain Volume Are Affected in Patients with Silver-Russell Syndrome.Semantic proximity Read ↗

Rebalancing polyamine levels to treat Snyder-Robinson syndrome.Semantic proximity Read ↗

Cortical gray matter structure in boys with Klinefelter syndrome.Semantic proximity Read ↗

Effects of sex chromosome aneuploidies on brain development: evidence from neuroimaging studies.Semantic proximity Read ↗

Altered neurodevelopment associated with mutations of RSK2: a morphometric MRI study of Coffin-Lowry syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.