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Article

Phylogeography of Francisella tularensis: global expansion of a highly fit clone.

Journal of bacteriology - 1 Apr 2009

Vogler Amy J, Birdsell Dawn, Price Lance B, Bowers Jolene R, Beckstrom-Sternberg Stephen M, Auerbach Raymond K, Beckstrom-Sternberg James S, Johansson Anders, Clare Ashley, Buchhagen Jordan L, Petersen Jeannine M, Pearson Talima, Vaissaire Josée, Dempsey Michael P, Foxall Paul, Engelthaler David M, Wagner David M, Keim Paul

Abstract excerpt

Francisella tularensis contains several highly pathogenic subspecies, including Francisella tularensis subsp. holarctica, whose distribution is circumpolar in the northern hemisphere. The phylogeography of these subspecies and their subclades was examined using whole-genome single nucleotide polymorphism (SNP) analysis, high-density microarray SNP genotyping, and real-time-PCR-based canonical SNP (canSNP) assays....

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Identifiers

PMID: 19251856
DOI: 10.1128/JB.01786-08
PMCID: PMC2668398

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