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Article

MGMT analysis at DNA, RNA and protein levels in glioblastoma tissue.

1 Apr 2009

Abstract excerpt

Evidence from several studies supports that the epigenetic, transcriptional and translational regulation and expression of O6-methylguanine-methyltransferase (MGMT) is relevant for prognostic and predictive considerations in glioblastoma patients. MGMT status is being used as a stratifying factor or eligibility criterion in ongoing and accruing clinical glioblastoma trials. In some cases, there is also interest...

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PMID: 19224454
DOI: 10.14670/hh-24.511

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