Article
Some of the people, some of the time: susceptibility to acute rheumatic fever.
Circulation - 10 Feb 2009
Bryant Penelope A, Robins-Browne Roy, Carapetis Jonathan R, Curtis Nigel
Abstract excerpt
Acute rheumatic fever is a major cause of heart disease in large parts of the world, but it remains unknown why only a small fraction of those who are infected with rheumatogenic group A streptococci develop an abnormal immune response that leads to acute rheumatic fever. An understanding of the mechanisms underlying host susceptibility can provide important insights into pathogenesis that in turn can inform new...
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