Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of a unique interaction between the complement regulatory protein factor H and the periodontal pathogen Treponema denticola.

Infection and immunity - 1 Apr 2009

McDowell John V, Huang Bernice, Fenno J Christopher, Marconi Richard T

Abstract excerpt

Treponema denticola, a spirochete associated with periodontitis, is abundant at the leading edge of subgingival plaque, where it interacts with gingival epithelia. T. denticola produces a number of virulence factors, including dentilisin, a protease which is cytopathic to host cells, and FhbB, a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chymotrypsin
Share to Complement Factor H
Share to Host-Pathogen Interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipoproteins

Share to Mutagenesis, Site-Directed

Share to Peptide Hydrolases

Share to Periodontal Diseases

Share to Virulence Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 19204088
DOI: 10.1128/IAI.01544-08
PMCID: PMC2663137

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19204088-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of a unique interaction between the complement regulatory protein factor H and the periodontal pathogen Treponema denticola.PMID 19204088Read ↗

Identification of the primary mechanism of complement evasion by the periodontal pathogen, Treponema denticolaSemantic proximity Read ↗

Demonstration of Factor H-Like Protein 1 Binding toTreponema denticola, a Pathogen Associated with Periodontal Disease in HumansSemantic proximity Read ↗

Analysis of the complement sensitivity of oral treponemes and the potential influence of FH binding, FH cleavage and dentilisin activity on the pathogenesis of periodontal disease.Semantic proximity Read ↗

Characterization of the Treponema denticola Virulence Factor Dentilisin.Semantic proximity Read ↗

Localization and pathogenic role of the cysteine protease dentipain in Treponema denticolaSemantic proximity Read ↗

Approaches to Understanding Mechanisms of Dentilisin Protease Complex Expression in Treponema denticolaSemantic proximity Read ↗

Treponema denticola chymotrypsin-like proteinase (CTLP) integrates spirochaetes within oral microbial communitiesSemantic proximity Read ↗

Virulence Factors of the Oral Spirochete Treponema denticolaSemantic proximity Read ↗

<i>Treponema denticola</i> dentilisin triggered TLR2/MyD88 activation upregulates a tissue destructive program involving MMPs via Sp1 in human oral cellsSemantic proximity Read ↗

Recruitment of Complement Factor H-Like Protein 1 Promotes Intracellular Invasion by Group A StreptococciSemantic proximity Read ↗

A surface‐exposed neuraminidase affects complement resistance and virulence of the oral spirochaete T reponema denticolaSemantic proximity Read ↗

Binding Properties and Adhesion-Mediating Regions of the Major Sheath Protein of<i>Treponema denticola</i>ATCC 35405Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.