Multiplicative interaction between the two major mechanisms of permethrin resistance, kdr and cytochrome P450‐monooxygenase detoxification, in mosquitoes

Abstract excerpt

Epistasis is the nonadditive interaction between different loci which contribute to a phenotype. Epistasis between independent loci conferring insecticide resistance is important to investigate as this phenomenon can shape the rate that resistance evolves and can dictate the level of resistance in the field. The evolution of insecticide resistance in mosquitoes is a growing and world-wide problem. The two major...

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