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Article

A single amino acid residue is responsible for species-specific incompatibility between CCT and alpha-actin.

FEBS letters - 18 Feb 2009

Altschuler G M, Dekker C, McCormack E A, Morris E P, Klug D R, Willison K R

Abstract excerpt

Actin is dependent on the type-II chaperonin CCT (chaperonin containing TCP-1) to reach its native state. In vitro, yeast CCT folds yeast and also mammalian cytoplasmic (beta/gamma) actins but is now found to be incapable of folding mammalian skeletal muscle alpha-actin. Arrest of alpha-actin on...

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Identifiers

PMID: 19183552
DOI: 10.1016/j.febslet.2009.01.031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19183552-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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