Article
X-linked mental retardation: focus on synaptic function and plasticity.
Journal of neurochemistry - 1 Apr 2009
Humeau Yann, Gambino Frédéric, Chelly Jamel, Vitale Nicolas
Abstract excerpt
Among mental disorders, mental retardation has been shown to be caused by various factors including a large array of genetic mutations. On the basis of remarkable progress, the emerging view is that defects in the regulation of synaptic activity and morphogenesis of dendritic spines are apparently common features associated with mutations in several genes implicated in mental retardation. In this review, we will...
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