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Profile of the Circulating DNA in Apparently Healthy Individuals

30 Jan 2009

Abstract excerpt

BACKGROUND: Circulating nucleic acids (CNAs) have been shown to have diagnostic utility in human diseases. The aim of this study was to sequence and organize CNAs to document typical profiles of circulating DNA in apparently healthy individuals. METHODS: Serum DNA from 51 apparently healthy humans was extracted, amplified, sequenced via pyrosequencing (454 Life Sciences/Roche Diagnostics), and categorized by (a)...

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PMID: 19181738
DOI: 10.1373/clinchem.2008.113597

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