Article
Collapsing glomerulopathy: beyond serendipity in mouse genetics.
Kidney international - 1 Feb 2009
Nelson Peter J, Bruggeman Leslie A
Abstract excerpt
Clinical correlates suggest that collapsing glomerulopathy results from the pathogenic interaction between patients' intractable genetic susceptibilities and environmental insults. When the environmental insults include a virus that introduces its own pathogenic genes, the interactions become more complex. Chan et al. combine reverse and forward genetic techniques in mice toward understanding this complexity with...
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