Molecular characterization and typing of enrofloxacin-resistant clinical isolates of Mycoplasma gallisepticum.

doi:10.1637/8386-063008-RESNOTE.1

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Article

Molecular characterization and typing of enrofloxacin-resistant clinical isolates of Mycoplasma gallisepticum.

Avian diseases - 1 Dec 2008

Lysnyansky I, Gerchman I, Perk S, Levisohn S

Abstract excerpt

Emergence of resistance to fluoroquinolones is mainly due to chromosomal mutations in genes encoding the subunits of the drug's target enzymes, DNA gyrase and topoisomerase IV, which are essential for DNA replication. The quinolone resistance-determining regions (QRDRs) of these genes were characterized in 25 Mycoplasma gallisepticum strains isolated from commercial poultry flocks during 1997-2007, which...

Topics

Amino Acid Substitution
Animals
Anti-Bacterial Agents
Base Sequence
Chickens
DNA Gyrase
DNA Topoisomerase IV
DNA, Bacterial
Drug Resistance, Bacterial
Enrofloxacin
Fluoroquinolones

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Bacterial

Molecular Sequence Data

Mutation

Mycoplasma gallisepticum

Random Amplified Polymorphic DNA Technique

Turkeys

Source

Open in PubMed

Identifiers

PMID: 19166064
DOI: 10.1637/8386-063008-RESNOTE.1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-19166064-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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