Article
Gene dosage compensation calibrates four regulatory RNAs to control Vibrio cholerae quorum sensing.
The EMBO journal - 18 Feb 2009
Svenningsen Sine L, Tu Kimberly C, Bassler Bonnie L
Abstract excerpt
Quorum sensing is a mechanism of cell-to-cell communication that allows bacteria to coordinately regulate gene expression in response to changes in cell-population density. At the core of the Vibrio cholerae quorum-sensing signal transduction pathway reside four homologous small RNAs (sRNAs), named the quorum regulatory RNAs 1-4 (Qrr1-4). The four Qrr sRNAs are functionally redundant. That is, expression of any...
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