Article
Mapping QTL affecting resistance to Marek's disease in an F6 advanced intercross population of commercial layer chickens.
BMC genomics - 14 Jan 2009
Heifetz Eliyahu M, Fulton Janet E, O'Sullivan Neil P, Arthur James A, Cheng Hans, Wang Jing, Soller Morris, Dekkers Jack C M
Abstract excerpt
BACKGROUND: Marek's disease (MD) is a T-cell lymphoma of chickens caused by the Marek's disease virus (MDV), an oncogenic avian herpesvirus. MD is a major cause of economic loss to the poultry industry and the most serious and persistent infectious disease concern. A full-sib intercross population, consisting of five independent families was generated by crossing and repeated intercrossing of two partially inbred...
Topics
- Alleles
- Animals
- Chickens
- Chromosome Mapping
- Crosses, Genetic
- Female
- Genetic Markers
- Genotype
- Immunity, Innate
- Marek Disease
- Microsatellite Repeats
- Polymorphism, Single Nucleotide
- Quantitative Trait Loci