Article
Mapping quantitative trait loci affecting susceptibility to Marek's disease virus in a backcross population of layer chickens.
Genetics - 1 Dec 2007
Heifetz E M, Fulton J E, O'Sullivan N P, Arthur J A, Wang J, Dekkers J C M, Soller M
Abstract excerpt
Marek's disease (MD), caused by the oncogenic MD avian herpes virus (MDV), is a major source of economic losses to the poultry industry. A reciprocal backcross (BC) population (total 2052 individuals) was generated by crossing two partially inbred commercial Leghorn layer lines known to differ in MDV resistance, measured as survival time after challenge with a (vv+) MDV. QTL affecting resistance were identified...
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