Article
Identification of microdeletions in candidate genes for cleft lip and/or palate.
Birth defects research. Part A, Clinical and molecular teratology - 1 Jan 2009
Shi Min, Mostowska Adrianna, Jugessur Astanand, Johnson Marla K, Mansilla Maria Adela, Christensen Kaare, Lie Rolv T, Wilcox Allen J, Murray Jeffrey C
Abstract excerpt
BACKGROUND: Genome-wide association studies are now used routinely to identify genes implicated in complex traits. The panels used for such analyses can detect single nucleotide polymorphisms and copy number variants, both of which may help to identify small deleted regions of the genome that may contribute to a particular disease. METHODS: We performed a candidate gene analysis involving 1,221 SNPs in 333...
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