Article
Correcting for ascertainment bias in the inference of population structure.
Bioinformatics (Oxford, England) - 15 Feb 2009
Guillot Gilles, Foll Matthieu
Abstract excerpt
BACKGROUND: The ascertainment process of molecular markers amounts to disregard loci carrying alleles with low frequencies. This can result in strong biases in inferences under population genetics models if not properly taken into account by the inference algorithm. Attempting to model this censoring process in view of making inference of population structure (i.e.identifying clusters of individuals) brings up...
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