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Article

<i>Leishmania</i> DNA Quantification by Real‐time PCR in Naturally Infected Dogs Treated with Miltefosine

1 Dec 2008

Abstract excerpt

A new drug that has just become available in India for treatment of human visceral leishmaniasis (VL) is miltefosine, an alkyphospholipid that was originally developed as an oral antineoplastic agent. Miltefosine is not only directly toxic for Leishmania parasite, but it also enhances both T cell and macrophage activation and production of microbicidal reactive nitrogen and oxygen intermediates. It is highly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19120249
DOI: 10.1196/annals.1428.018

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