Placentation abnormalities in the pathophysiology of preeclampsia

Abstract excerpt

Preeclampsia, a pregnancy-specific syndrome of hypertension and proteinuria, is one of the leading causes of perinatal morbidity and mortality. Although the initiating factor is unknown, a clearer picture regarding the network mechanisms of preeclampsia has begun to emerge during the past few years. The pathogenesis of preeclampsia can be described as having two stages. The first stage of preeclampsia involves...