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Article

Hemolysis and hyperhomocysteinemia caused by cobalamin deficiency: three case reports and review of the literature.

Journal of hematology & oncology - 18 Dec 2008

Acharya Utkarsh, Gau Jen-Tzer, Horvath William, Ventura Paolo, Hsueh Chung-Tsen, Carlsen Wayne

Abstract excerpt

Concurrent hemolysis in patients with vitamin B12 deficiency is a well-recognized phenomenon and has been attributed to intramedullary destruction of erythrocytes (ineffective erythropoiesis). Recent studies revealed that homocysteine increased the risk of hemolysis in vitamin B12 deficiency in vitro and there is a high frequency (30%) of vitamin B12 deficiency in asymptomatic patients with homozygous methylene...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Source

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Identifiers

PMID: 19094231
DOI: 10.1186/1756-8722-1-26
PMCID: PMC2626597

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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