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Article

Regulation of P450 oxidoreductase by gonadotropins in rat ovary and its effect on estrogen production.

Reproductive biology and endocrinology : RB&E - 16 Dec 2008

Inaoka Yoshihiko, Yazawa Takashi, Mizutani Tetsuya, Kokame Koichi, Kangawa Kenji, Uesaka Miki, Umezawa Akihiro, Miyamoto Kaoru

Abstract excerpt

BACKGROUND: P450 oxidoreductase (POR) catalyzes electron transfer to microsomal P450 enzymes. Its deficiency causes Antley-Bixler syndrome (ABS), and about half the patients with ABS have ambiguous genitalia and/or impaired steroidogenesis. POR mRNA expression is up-regulated when mesenchymal stem cells (MSCs) differentiate into steroidogenic cells, suggesting that the regulation of POR gene expression is...

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Identifiers

PMID: 19077323
DOI: 10.1186/1477-7827-6-62
PMCID: PMC2647926

Genes

POR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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