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Article

Macrolide therapy targets a specific phenotype in respiratory medicine: from clinical experience to basic science and back.

Inflammation & allergy drug targets - 1 Dec 2008

Vanaudenaerde Bart M, Vos Robin, Meyts Isabelle, De Vleeschauwer Stephanie I, Verleden Stijn E, Widyastuti-Willems Anna, Wuyts Wim A, Van Raemdonck Dirk E, Hoet Peter H, Dupont Lieven J, Nemery Benoit, Verleden Geert M

Abstract excerpt

For centuries a quest has been going on for the "holy grail" in respiratory medicine: a treatment for numerous devastating chronic lung disorders. Yet, it is only a decade ago that pharmacological interference with the activation of the innate immune system by a macrolide antibiotic silently moved into everyday clinical practice. Macrolides, with their unique molecular structure built around a lactone ring, are...

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Identifiers

PMID: 19075792
DOI: 10.2174/187152808786848414

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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