Article
Association of a bacteriophage with meningococcal disease in young adults.
PloS one - 1 Jan 2008
Bille Emmanuelle, Ure Roisin, Gray Stephen J, Kaczmarski Edward B, McCarthy Noel D, Nassif Xavier, Maiden Martin C J, Tinsley Colin R
Abstract excerpt
Despite being the agent of life-threatening meningitis, Neisseria meningitidis is usually carried asymptomatically in the nasopharynx of humans and only occasionally causes disease. The genetic bases for virulence have not been entirely elucidated and the search for new virulence factors in this species is hampered by the lack of an animal model representative of the human disease. As an alternative strategy we...
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