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Article

WHIM syndrome: congenital immune deficiency disease.

Current opinion in hematology - 1 Jan 2009

Kawai Toshinao, Malech Harry L

Abstract excerpt

PURPOSE OF REVIEW: Warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome is characterized by susceptibility to human papilloma virus infection-induced warts and carcinomas; neutropenia, B-cell lymphopenia and hypogammaglobulinema-related infections; and bone marrow myelokath...

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Topics

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Share to Agammaglobulinemia
Share to CXCL12 gene
Share to Immunologic Deficiency Syndromes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, CXCR4

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Source

Open in PubMed Open full text

Identifiers

PMID: 19057201
DOI: 10.1097/MOH.0b013e32831ac557
PMCID: PMC2673024

Genes

CXCR4
CXCL12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19057201-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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WHIM syndrome: congenital immune deficiency disease.PMID 19057201Read ↗

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CXCL12/CXCR4-Axis Dysfunctions: Markers of the Rare Immunodeficiency Disorder WHIM SyndromeSemantic proximity Read ↗

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Clinical and genetic features of Warts, Hypogammaglobulinemia, Infections and Myelokathexis (WHIM) syndrome.Semantic proximity Read ↗

WHIM syndromes with different genetic anomalies are accounted for by impaired CXCR4 desensitization to CXCL12Semantic proximity Read ↗

WHIM syndrome caused by a single amino acid substitution in the carboxy-tail of chemokine receptor CXCR4.Semantic proximity Read ↗

Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease.Semantic proximity Read ↗

Defect of plasmacytoid dendritic cells in warts, hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome patients.Semantic proximity Read ↗

Genetics on a <scp>WHIM</scp>Semantic proximity Read ↗

How I treat warts, hypogammaglobulinemia, infections, and myelokathexis syndrome.Semantic proximity Read ↗

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