Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Status epilepticus in children with Alpers' disease caused by POLG1 mutations: EEG and MRI features.

Epilepsia - 1 Jun 2009

Wolf Nicole I, Rahman Shamima, Schmitt Bernhard, Taanman Jan-Willem, Duncan Andrew J, Harting Inga, Wohlrab Gabriele, Ebinger Friedrich, Rating Dietz, Bast Thomas

Abstract excerpt

PURPOSE: Refractory convulsive status epilepticus in infancy and childhood is a rare emergency situation. Metabolic disorders frequently underlie this condition, in particular Alpers' disease caused by POLG1 mutations. Status epilepticus may be the first symptom. A pathognomonic electroencephalog...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diffuse Cerebral Sclerosis of Schilder
Share to DNA-Directed DNA Polymerase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Polymerase gamma

Share to Electroencephalography

Share to Magnetic Resonance Imaging

Share to Magnetic Resonance Spectroscopy

Share to Status Epilepticus

Share to Tritium

Source

Identifiers

PMID: 19054397
DOI: 10.1111/j.1528-1167.2008.01877.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19054397-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Status epilepticus in children with Alpers' disease caused by POLG1 mutations: EEG and MRI features.PMID 19054397Read ↗

Partial status epilepticus - rapid genetic diagnosis of Alpers' disease.Semantic proximity Read ↗

Alpers syndrome with mutations in POLG: clinical and investigative features.Semantic proximity Read ↗

The spectrum of epilepsy caused by POLG mutations.Semantic proximity Read ↗

Prospective study of POLG mutations presenting in children with intractable epilepsy: prevalence and clinical features.Semantic proximity Read ↗

POLG1 manifestations in childhood.Semantic proximity Read ↗

POLG DNA testing as an emerging standard of care before instituting valproic acid therapy for pediatric seizure disorders.Semantic proximity Read ↗

Epilepsy due to mutations in the mitochondrial polymerase gamma (POLG) gene: A clinical and molecular genetic review.Semantic proximity Read ↗

Case Report: Re-investigating recurrent Refractory Status Epilepticus revealed POLG-Related Mitochondrial DiseaseSemantic proximity Read ↗

Diagnosis of pyridoxine-dependent epilepsy in an adult presenting with recurrent status epilepticus.Semantic proximity Read ↗

POLG1 mutations cause a syndromic epilepsy with occipital lobe predilection.Semantic proximity Read ↗

Electroencephalographic and seizure manifestations of pyridoxal 5'-phosphate-dependent epilepsy.Semantic proximity Read ↗

Phenotypic and genotypic variability in Alpers syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.